doTERRA MetaPWR Metabolic Blend and Fat Cells
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Many of you are looking for doTERRA MetaPWR Metabolic Blend products to support weight loss. That is why we are bringing you an article from doTERRA’s US site about the MetaPWR range. Here you can read about doTERRA’s own study from a slightly more scientific perspective.
During the development of MetaPWR Metabolic Blend, doTERRA carried out a series of preliminary studies before the clinical trial. Although the findings still need to be confirmed by clinical research, the results were extremely promising!
doTERRA previously had a blend that contained the same essential oils as MetaPWR Metabolic Blend: grapefruit, lemon, peppermint, ginger, and cinnamon bark. This blend was Slim & Sassy® .
Slim & Sassy contained the same essential oils as MetaPWR, but in different ratios. At doTERRA, they wanted to find out whether optimizing the ratios of the essential oils could produce an even better metabolism-supporting effect.
Examining fat cells
Human adipocytes (fat cells in adipose tissue) were taken through a maturation process. When a fat cell is exposed to different stimuli, the cell matures and accumulates fat droplets inside. In the image, you can see that by day 14 small spheres appear inside each fat cell.

On the left, immature cells can be seen; they are flat and almost free of fat.
On the right are cells filled with fat droplets, which are significantly larger.
Dose-response study
A dose-response study was carried out using different versions of MetaPWR Metabolic Blend and Slim & Sassy. The image below shows the results obtained when the adipocytes were treated with the original Slim & Sassy essential oil blend .

It can be observed that it inhibited fat accumulation in these human fat cells, even at low doses. This was exciting news during doTERRA’s research, although they were not surprised: Slim & Sassy performed exceptionally well in regulating fat accumulation.

Testing a different essential oil ratio
They then used a different composition (ratio) made from the same five essential oils. It can be seen that this version was not as effective, as Slim & Sassy at inhibiting fat accumulation. Although it had an effect, the results were less convincing.

MetaPWR Metabolic Blend results
Finally, here are the results of the study carried out with the current MetaPWR Metabolic Blend formula. This essential oil blend and ratio proved to be the most effective. It was surprising to see that the desired effect was significantly enhanced by using the optimized ratio. It is clearly visible that by day 14 the fat cells were much less maturethan in the control group.*

This bar chart presents the three studies shown above side by side. Different strengths, ratios, and blends were tested until they arrived at the composition we now know as MetaPWR . This proved to be the most effective version, which is why it became the official formula.
You can also find the products in our shop under doTERRA MetaPWR products.
- MetaPWR™ Essential Oil
- MetaPWR™ Softgels
- MetaPWR™ Assist
- MetaPWR™ Beadlets
- MetaPWR™ Mito2Max
- MetaPWR Advantage
- MetaPWR Recharge in wild strawberry flavor
- MetaPWR system kit
* These statements have not been evaluated by the U.S. Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease.